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产品名称
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Bepotastine Besilate
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英文名称
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Bepotastine Besilate
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应用
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选择性的组胺1 (H1)受体拮抗剂，pIC50为5.7。
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规格或纯度
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98%
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别名
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N/A;苯磺酸贝托司汀
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英文别名
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N/A;1-Piperidinebutanoic acid, 4-[(S)-(4-chlorophenyl)-2-pyridinylmethoxy]-, benzenesulfonate (1:1);(+)-(S)-4-[4-[1-(4-Chlorophenyl)-1-(2-pyridyl)methoxy]piperidin-1-yl]butyric acid benzenesulfonate
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运输条件
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超低温冰袋运输
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生化机理
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Bepotastine Beslilate also suppresses some allergic inflammatory processes such as allergic rhinitis, chronic urticaria or pruritus associated with skin conditions (eczema/dermatitis, prurigo or pruritus cutaneus).Bepotastine Beslilate (Bepreve) is useful for allergic conjunctivitis.Selective H 1 receptor antagonist. Stabilizes mast cell function. Inhibits eosinophilic infiltration. Inhibits IL-5 production, LTB4 and LTD4 activity. Shows antiallergic and antipruritic effects in vivo. Orally active.
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